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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP14
All Species:
34.55
Human Site:
Y333
Identified Species:
50.67
UniProt:
P54578
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54578
NP_001032411.1
494
56069
Y333
I
Q
M
V
R
F
F
Y
K
E
K
E
S
V
N
Chimpanzee
Pan troglodytes
P60051
493
55922
Y333
I
Q
M
V
R
F
F
Y
K
E
K
E
S
V
N
Rhesus Macaque
Macaca mulatta
XP_001090667
458
52239
N305
Y
K
E
K
E
S
V
N
A
K
V
L
K
D
V
Dog
Lupus familis
XP_537306
545
61461
Y384
I
Q
M
V
R
F
F
Y
K
E
K
E
S
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA1
493
55983
Y333
I
Q
M
V
R
F
F
Y
K
E
K
E
S
V
N
Rat
Rattus norvegicus
NP_001008302
493
55958
Y333
I
Q
M
V
R
F
F
Y
K
E
K
E
S
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519267
431
48760
A278
K
E
K
G
S
V
N
A
K
V
L
K
D
V
K
Chicken
Gallus gallus
XP_419150
492
55612
Y331
I
Q
M
V
R
F
F
Y
K
E
K
E
S
V
N
Frog
Xenopus laevis
Q6GNI6
523
60030
L329
F
W
D
I
S
L
D
L
P
G
S
S
T
P
F
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
P337
V
V
N
G
D
S
H
P
S
G
A
T
T
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609377
475
53689
Y320
V
Q
F
V
R
F
Q
Y
K
G
K
E
G
I
N
Honey Bee
Apis mellifera
XP_395043
497
56311
Y328
I
Q
F
V
R
F
Y
Y
K
E
K
E
A
I
N
Nematode Worm
Caenorhab. elegans
Q17361
489
55859
N310
Y
K
E
S
T
K
T
N
A
K
I
L
K
S
V
Sea Urchin
Strong. purpuratus
XP_786966
516
58357
Y334
V
Q
F
V
R
F
Y
Y
K
E
K
E
A
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q949Y0
482
53677
W313
V
Q
F
V
R
F
F
W
K
R
E
S
N
Q
K
Baker's Yeast
Sacchar. cerevisiae
P43593
499
57092
W319
V
Q
Y
V
R
F
F
W
K
R
S
T
N
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.5
89.9
N.A.
96.7
96.5
N.A.
80.3
90.4
21.4
20.1
N.A.
54.6
61.7
41.9
61
Protein Similarity:
100
99.8
92.7
90.2
N.A.
98.5
98.7
N.A.
83.8
94.9
39
38.7
N.A.
71.2
80.2
61.1
76.5
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
13.3
100
0
0
N.A.
60
73.3
0
60
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
26.6
100
13.3
20
N.A.
73.3
93.3
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
13
0
7
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
0
7
0
0
0
0
0
7
7
0
% D
% Glu:
0
7
13
0
7
0
0
0
0
50
7
57
0
0
0
% E
% Phe:
7
0
25
0
0
69
50
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
13
0
0
0
0
0
19
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
44
0
0
7
0
0
0
0
0
0
7
0
0
19
0
% I
% Lys:
7
13
7
7
0
7
0
0
75
13
57
7
13
7
19
% K
% Leu:
0
0
0
0
0
7
0
7
0
0
7
13
0
7
0
% L
% Met:
0
0
38
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
7
13
0
0
0
0
13
0
50
% N
% Pro:
0
0
0
0
0
0
0
7
7
0
0
0
0
7
0
% P
% Gln:
0
69
0
0
0
0
7
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
69
0
0
0
0
13
0
0
0
0
0
% R
% Ser:
0
0
0
7
13
13
0
0
7
0
13
13
38
7
7
% S
% Thr:
0
0
0
0
7
0
7
0
0
0
0
13
13
0
7
% T
% Val:
32
7
0
69
0
7
7
0
0
7
7
0
0
44
13
% V
% Trp:
0
7
0
0
0
0
0
13
0
0
0
0
0
0
0
% W
% Tyr:
13
0
7
0
0
0
13
57
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _